Neutropenia management
نویسندگان
چکیده
منابع مشابه
Management of Febrile Neutropenia
Bacterial Pathogens Bacteria are the predominant organisms. In the late 1950’s/early 1960’s Gram+ve organisms were the commonest, particularly Staphylococcus aureus. The late 1960’s/early 1970’s were typified by Gram-ve of gastrointestinal tract origin, particularly Escherischia coli, Klebsiella spp and Pseudomonas spp. By the 1990’s Staphylococcus spp including coagulase negative organisms, St...
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Despite major advances in prevention and treatment, febrile neutropenia (FN) remains one of the most feared complications of cancer chemotherapy, and is a major cause of morbidity, healthcare resource use, and results in delays and dose reductions in chemotherapy which compromise efficacy. Mortality from FN has diminished steadily but remains significant. Overall mortality rates are 5% in patie...
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chemotherapy remains the cornerstone of cancer therapy. In most cases bone marrow suppression represents the doselimiting toxicity of these drugs. Druginduced DNA damage at the level of bone marrow progenitor cells results in a fall in circulating neutrophil count. Patients with neutropenia are at increased risk of infection and sepsis.1 The timing of neutropenia is generally predictable; it ty...
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This study aimed to provide an evidence-based guideline for the clinical management of febrile neutropenia in children with cancer. In this narrative review, the most recently published sources of information on febrile neutropenia consisting of textbooks and articles, have been reviewed. We focused on the more recent data about diagnosis, treatment and management in children through the use o...
متن کاملEvaluation and management of patients with isolated neutropenia.
Neutropenia, defined as an absolute neutrophil count (ANC) <1.5 × 10(9)/L, encompasses a wide range of diagnoses, from normal variants to life-threatening acquired and congenital disorders. This review addresses the diagnosis and management of isolated neutropenia, not multiple cytopenias due to splenomegaly, bone marrow replacement, or myelosuppression by chemotherapy or radiation. Laboratory ...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2006
ISSN: 0923-7534
DOI: 10.1093/annonc/mdl243